What is the charge? Eating a meal, a succulent Chinese meal?

View the Project on GitHub ntustison/CV

Nick Tustison

Curriculum Vitae (.pdf)

Orcid ID

Google scholar


Professional Appointments

Academic Service

2018-present: Insight Software Consortium Council (secretary) 2012-present: SPIE Medical Imaging program committee


2012-present: Frontiers Review Editorial Board. May 2013-present: Frontiers in Neuroinformatics: Guest Editor, Neuroinformatics with the Insight ToolKit.

Reviewer Duties

Academic Radiology American Journal of Neuroradiology Annals of Biomedical Engineering Artificial Intelligence in Medicine Biomedical Signal Processing and Control Computers in Biology and Medicine Computerized Medical Imaging and Graphics Focused Ultrasound Foundation ad hoc grant reviewer Human Brain Mapping Image and Vision Computing International Journal of Pattern Recognition and Artificial Intelligence IEEE Transactions on Cybernetics IEEE Transactions on Medical Imaging IEEE Transactions on Pattern Analysis and Machine Intelligence IEEE Transactions on Biomedical Engineering Insight Journal International Conf. on Medical Image Computing and Computer Assisted Intervention International Journal of Biomedical Imaging International Journal of Computer Vision International Workshop on Medical Imaging and Augmented Reality IEEE International Symposium on Biomedical Imaging: From Nano to Macro Journal of Computed Tomography Journal of Electronic Imaging Journal of Magnetic Resonance Imaging Journal of Neurotrauma Journal of the Optical Society of America A MRI Magnetic Resonance in Medicine Medical Physics Medical Image Analysis Neurobiology of Aging NeuroImage NeuroImage: Clinical Neuroradiology Neuroscience and Biobehavioral Reviews PLOS ONE Psychiatric Research: Neuroimaging Respirology Scientific Reports SIAM Journal on Imaging Sciences

Invited Talks/Participation

Feb 2012: SPIE Workshop: Medical Imaging, Open source tools for medical image analysis. Sep 2012: MICCAI, provided canonical registrations for Grand Challenge and Workshop on Multi-Atlas Labeling. Sep 2013: MICCAI, provided canonical registrations for SATA challenge workshop. May 2015: CREATE-MIA Summer Workshop, ANTs Workshop. Oct 2015: MICCAI, SimpleITK tutorial. May 2019: ICERM, Brown University, Introduction to the ANTs Ecosystem. Jun 2019: SMI, Collaborative Case Study, Longitudinal mapping of cortical thickness measurements: an ADNI-based evaluation study.

Computer Skills


Areas of research interest

Journal Publications


94. Batool Rizvi, Mithra T Sathishkumar, Soyun Kim, Freddie Márquez, Steven J. Granger, Myra S. Larson, Blake A. Miranda, Martina K. Hollearn, L. McMillan, B. Nan, N. Tustison, P. Lao, A. Brickman, Dana E. Greenia, M. Corrada, C. Kawas, and M. Yassa. Posterior white matter hyperintensities are associated with reduced medial temporal lobe subregional integrity and long-term memory in older adults. (biorxiv)

93. Adam Kimbler, Dana McMakin, Nicholas J. Tustison, and Aaron T. Mattfeld. Differential effects of emotional valence on mnemonic performance with greater hippocampal maturity. (biorxiv)

92. Jesse W. Birchfield, Nicholas J. Tustison, and Andrew J. Holbrook. Synthesizing longitudinal cortical thickness estimates with a flexible and hierarchical multivariate measurement-error model. (arxiv)

91. Raghav Mehta, Angelos Filos, Ujjwal Baid, Chiharu Sako, Richard McKinley, Michael Rebsamen, Katrin Dätwyler, Raphael Meier, Piotr Radojewski, Gowtham Krishnan Murugesan, Sahil Nalawade, Chandan Ganesh, Ben Wagner, Fang F. Yu, Baowei Fei, Ananth J. Madhuranthakam, Joseph A. Maldjian, Laura Daza, Catalina Gómez, Pablo Arbeláez, Chengliang Dai, Shuo Wang, Hadrien Raynaud, Yuanhan Mo, Elsa Angelini, Yike Guo, Wenjia Bai, Subhashis Banerjee, Linmin Pei, Murat AK, Sarahi Rosas-González, Illyess Zemmoura, Clovis Tauber, Minh H. Vu, Tufve Nyholm, Tommy Löfstedt, Laura Mora Ballestar, Veronica Vilaplana, Hugh McHugh, Gonzalo Maso Talou, Alan Wang, Jay Patel, Ken Chang, Katharina Hoebel, Mishka Gidwani, Nishanth Arun, Sharut Gupta, Mehak Aggarwal, Praveer Singh, Elizabeth R. Gerstner, Jayashree Kalpathy-Cramer, Nicolas Boutry, Alexis Huard, Lasitha Vidyaratne, Md Monibor Rahman, Khan M. Iftekharuddin, Joseph Chazalon, Elodie Puybareau, Guillaume Tochon, Jun Ma, Mariano Cabezas, Xavier Llado, Arnau Oliver, Liliana Valencia, Sergi Valverde, Mehdi Amian, Mohammadreza Soltaninejad, Andriy Myronenko, Ali Hatamizadeh, Xue Feng, Quan Dou, Nicholas Tustison, Craig Meyer, Nisarg A. Shah, Sanjay Talbar, Marc-Andr Weber, Abhishek Mahajan, Andras Jakab, Roland Wiest, Hassan M. Fathallah-Shaykh, Arash Nazeri, Mikhail Milchenko, Daniel Marcus, Aikaterini Kotrotsou, Rivka Colen, John Freymann, Justin Kirby, Christos Davatzikos, Bjoern Menze, Spyridon Bakas, Yarin Gal, Tal Arbel. QU-BraTS: MICCAI BraTS 2020 Challenge on Quantifying Uncertainty in Brain Tumor Segmentation — Analysis of Ranking Scores and Benchmarking Results. The Journal of Machine Learning for Biomedical Imaging. Accepted

90. Danni Tu, Manu S. Goyal, Jordan D. Dworkin, Samuel Kampondeni, Lorenna Vidal, Eric Biondo-Savin, Sandeep Juvvadi, Prashant Raghavan, Jennifer Nicholas, Karen Chetcuti, Kelly Clark, Timothy Robert-Fitzgerald, Theodore D. Satterthwaite, Paul Yushkevich, Christos Davatzikos, Guray Erus, Nicholas J. Tustison, Douglas G. Postels, Terrie E. Taylor, Dylan S. Small, and Russell T. Shinohara. Automated Analysis of Low-Field Brain MRI in Cerebral Malaria. Biometrics. (pubmed)

89. Nazek Queder, Michael J. Phelan, Lisa Taylor, Nicholas Tustison, Eric Doran, Christy Hom, Dana Nguyen, Florence Lai, Margaret Pulsifer, Julie Price, William C. Kreisl, Diana H. Rosas, Sharon Krinsky-McHale, Adam Brickman, Michael A. Yassa, Nicole Schupf, Wayne Silverman, Ira T. Lott, and David B. Keator. Joint-label fusion brain atlases for dementia research in down syndrome. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring. (pubmed)

88. Zhuang Song, Anithapriya Krishnan, Laura Gaetano, Nicholas J. Tustison, David Clayton, Alex de Crespigny, Thomas Bengtsson, Xiaoming Jia, and Richard A.D. Carano. Deformation-based morphometry identifies deep brain structures protected by ocrelizumab. NeuroImage: Clinical. (pubmed)

87. Andrew A. Chen, Joanne C. Beer, Nicholas J. Tustison, Philip A. Cook, Russell T. Shinohara, Haochang Shou, for the Alzheimer’s Disease Neuroimaging Initiative. Mitigating Site Effects in Covariance for Machine Learning in Neuroimaging Data. Human Brain Mapping, 43(4):1179-1195, Mar 2022. (pubmed)

86. Dana L McMakin, Adam Kimbler, Nicholas J. Tustison, Jeremy W Pettit, and Aaron T. Mattfeld. Negative Overgeneralization is Associated with Pattern Completion in Peripubertal Youth. Social Cognitive and Affective Neuroscience, 17(2):231-240, Feb 2022. (pubmed)


85. Andrew T. Grainger, Arun Krishnaraj, Michael H. Quinones, Nicholas J. Tustison, Samantha Epstein, Daniela Fuller, Aakash Jha, Kevin L. Allman, Weibin Shi. Deep learning-based quantification of abdominal subcutaneous and visceral fat volume on CT images. Academic Radiology, 28(11):1481-1487, Nov 2021. (pubmed)

84. Mu He, Kun Qing, Nicholas J. Tustison, Zach Beaulac, Tabitha W. King, Thomas B. Huff, Mikell Paige, Kranthikiran Earasi, Roselove Nunoo-Asare, Sarah Struchen, Marie Burdick, Zhimin Zhang, Alan Ropp, Grady W. Miller, James T. Patrie, Jaime F. Mata, John P. Mugler III, and Yun M. Shim. Characterizing gas exchange physiology in healthy young electronic-cigarette users with hyperpolarized 129Xe MRI: a pilot study. International Journal of Chronic Obstructive Pulmonary Disease, 16:3183-3187, Nov 2021. (pubmed)

83. Nicholas J. Tustison, Talissa A. Altes, Kun Qing, Mu He, G. Wilson Miller, Brian B. Avants, Yun M. Shim, James C. Gee, John P. Mugler III, and Jaime F. Mata. Image- vs. histogram-based considerations in semantic segmentation of pulmonary hyperpolarized gas images. Magnetic Resonance in Medicine, 86(5):2822-2836, Nov 2021. (pubmed)

82. Jaime Mata, Steven Guan, Kun Qing, Nicholas Tustison, Yun Shim, John P Mugler 3rd, Talissa Altes, Jhosep Huaromo, Borna Mehrad. Evaluation of Regional Lung Function in Pulmonary Fibrosis with Xenon-129 MRI. Tomography, 7(3):452-465, Sep 2021. (pubmed)

81. William Teague, Jaime Mata, Kun Qing, Nicholas Tustison, John Mugler, Craig Meyer, Eduard de Lange, Michael Shim, Kristin Wavell, Talissa Altes. Measures of Ventilation Heterogeneity Mapped with Hyperpolarized Helium-3 (HHe-3) MRI Demonstrate a T2-High Phenotype in Asthma. Pediatric Pulmonology, 56(6):1440-1448, Jun 2021. (pubmed)

80. Nicholas J. Tustison, Philip A. Cook, Andrew J. Holbrook, Hans J. Johnson, John Muschelli, Gabriel A. Devenyi, Jeffrey T. Duda, Sandhitsu R. Das, Nicholas C. Cullen, Daniel L. Gillen, Michael A. Yassa, James R. Stone, James C. Gee, and Brian B. Avants for the Alzheimer’s Disease Neuroimaging Initiative. The ANTsX ecosystem for quantitative biological and medical imaging. Scientific Reports. 11(1):9068, Apr 2021. (pubmed)

79. Brian B. Avants, Nicholas J. Tustison, and James R. Stone. Interpretable, similarity-driven multi-view embeddings from high-dimensional biomedical data. Nature Computational Science, 1(2):143-152, Feb 2021. (pubmed)


78. James Stone, Brian Avants, Nicholas Tustison, Eric Wasserman, Jessica Gill, Elena Polejaeva, Kristine Dell, Walter Carr, Angela Yarnell, Matthew LoPresti, Peter Walker, Meghan O’Brien, Natalie Domeisen, Alycia Quick, Claire Modica, John D. Hughes, Francis Haran, Carl Goforth, and Stephen Ahlers. Functional and structural neuroimaging correlates of repetitive low-level blast exposure in career breachers. Journal of Neurotrauma, 37(23):2468-2481, Dec 2020. (pubmed)

77. Lukasz Myc, Kun Qing, Mu He, Nicholas Tustison, Zixuan Lin, Ani W Manichaikul, James Patrie, Joanne Cassani, Roselove N Nunoo-Asare, Yong Huang, Zaid Obaida, Sina Tafti, Alan M Ropp, Grady Wilson Miller, Jaime Mata, Talissa Altes, John Mugler, and Y Michael Shim. Characterisation of gas exchange in COPD with dissolved-phase hyperpolarised xenon-129 MRI. Thorax, 76(2):178-181, Nov 2020. (pubmed)

76. Joanne C. Beer, Nicholas J. Tustison, Philip A. Cook, Yvette I. Sheline, Russell T. Shinohara, Kristin A. Linn, for the Alzheimer’s Disease Neuroimaging Initiative. Longitudinal ComBat: A Method for Harmonizing Longitudinal Multi-scanner Imaging Data, NeuroImage, 220:117129, Oct 2020. (pubmed)

75. Erin D. Bigler, Marc Skiles, Benjamin S.C. Wade, Tracy J. Abildskov, Nicholas J. Tustison, Randall S. Scheibel, Mary R. Newsome, Andrew R. Mayer, James R. Stone, Brian A. Taylor, David F. Tate, William C. Walker, Harvey S. Levin, and Elisabeth A. Wilde. FreeSurfer 5.3 versus 6.0: Are volumes comparable? A Chronic Effects of Neurotrauma Consortium Study, Brain Imaging and Behavior, 14(5):1318-1327, Oct 2020. (pubmed)

74. J. Sebastian Giudice, Ahmed Alshareef, Taotao Wu, Christina A. Gancayco, Kristen A. Reynier, Nicholas J. Tustison, T. Jason Druzgal, and Matthew B. Panzer. An Image Registration-Based Morphing Technique for Generating Subject-Specific Brain Finite Element Models, Annals of Biomedical Engineering, 48(10):2412-2424, Oct 2020. (pubmed)

73. Eric Aliotta, Sunil W Dutta, Xue Feng, Nicholas J Tustison, Prem P Batchala, David Schiff, Maria-Beatriz Lopes, Rajan Jain, Jason Druzgal, Sugoto Mukherjee, Sohil H Patel. Automated Apparent Diffusion Coefficient Analysis for Genotype Prediction in Lower Grade Glioma: Association with the T2-FLAIR Mismatch Sign. Journal of Neuro-Oncology, 149(2):325-335, Sep 2020. (pubmed)

72. Andrew Holbrook, Nicholas Tustison, Freddie Marquez, Jared Roberts, Michael A. Yassa, Daniel Gillen. Anterolateral entorhinal cortex thickness as a new biomarker for early detection of Alzheimer’s disease. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 12(1):e12068, August 2020. (pubmed)

71. Chase S Hall, James D Quirk, Charles W Goss, Daphne Lew, Jim Kozlowski, Robert P Thomen, Jason C Woods, Nicholas J Tustison, John P Mugler 3rd, Lora Gallagher, Tammy Koch, Ken B Schechtman, Iulian C Ruset, F William Hersman, Mario Castro. Single-Session Bronchial Thermoplasty Guided by 129Xe Magnetic Resonance Imaging, American Journal of Respiratory and Critical Care Medicine, 202(4):524-534, August 2020. (pubmed)

70. Cuneyt Yilmaz, D. Merrill Dane, Nicholas Tustison, Gang Song, James C. Gee, and Connie W. Hsia. In vivo imaging of canine lung deformation: Effects of posture, pneumonectomy, and inhaled erythropoietin, Journal of Applied Physiology, 128(5):1093-1105, May 2020. (pubmed)

69. Xue Feng, Nicholas James Tustison, Sohil H. Patel, and Craig H. Meyer. Brain Tumor Segmentation using an Ensemble of 3D U-Nets and Overall Survival Prediction using Radiomic Features, Frontiers in Computational Neuroscience, 14:25, Apr 2020. (pubmed)


68. Duc M. Nguyen, Michael A. Yassa, Nicholas J. Tustison, Jared M. Roberts, Alexandra Kulikova, Alyson Nakamura, Elena I. Ivleva, Erin Van Enkevort, and E. Sherwood Brown, The Relationship Between Cumulative Exogenous Corticosteroid Exposure and Volumes of Hippocampal Subfields and Surrounding Structures. Journal of Clinical Psychopharmacology, 39(6):653-657, Nov/Dec 2019. (pubmed)

67. Nicholas J. Tustison, Brian B. Avants, and James C. Gee. Learning image-based spatial transformations via convolutional neural networks: a review, Magnetic Resonance Imaging, 64:142-153, Dec 2019. (pubmed)

66. E. Brown, Alexandra Kulikova, Erin Van Enkevort, Alyson Nakamura, Elena Ivleva, Nicholas Tustison, Jared Roberts, Michael Yassa, Changho Choi, Alan Frol, David Khan, Miguel Vazquez, Traci Holmes, and Kendra Malone. A Randomized Trial of an NMDA Receptor Antagonist for Reversing Corticosteroid Effects on the Human Hippocampus, Neuropsychopharmacology, 44(13):2263-2267, Dec 2019. (pubmed)

65. Neda Jahanshad, Joshua Faskowitz, Gennady Roshchupkin, Derrek P. Hibar, Boris A. Gutman, Nicholas J. Tustison, Hieab H.H. Adams, Wiro J. Niessen, Meike W. Vernooij, M. Arfan Ikram, Marcel P. Zwiers, Alejandro Arias Vasquez, Barbara Franke, Jennifer L. Kroll, Benson Mwangi, Jair C. Soares, Alex Ing, Sylvane Desrivieres, Gunter Schumann, Narelle K. Hansell, Greig I. de Zubicaray, Katie L. McMahon, Nicholas G. Martin, Margaret J. Wright, Paul M. Thompson and the Alzheimer’s Disease Neuroimaging Initiative. Multi-Site meta-analysis of morphometry, IEEE/ACM Transactions on Computational Biology & Bioinformatics, 16(5):1508-1514, Oct 2019. (pubmed)

64. Nicholas J. Tustison, Andrew J. Holbrook, Brian B. Avants, Jared M. Roberts, Philip A. Cook, Zachariah M. Reagh, Jeffrey T. Duda, James R. Stone, Daniel L. Gillen, and Michael A. Yassa for the Alzheimer’s Disease Neuroimaging Initiative. Longitudinal mapping of cortical thickness measurements: an ADNI-based evaluation study, Journal of Alzheimer’s Disease, 71(1):165-183, Sep 2019. (pubmed)

63. G. Allan Johnson, Nian Wang, Robert J. Anderson, Min Chen, Gary P Cofer, James C. Gee, Forrest Pratson, Nicholas J. Tustison, and Leonard White. Whole Mouse Brain Connectomics, The Journal of Comparative Neurology, 527(13):2146-2157, Sep 2019. (pubmed)

62. Neha Sinha, Zachariah M. Reagh, Nicholas J. Tustison, Chelsie N. Berg, Ashlee Shaw, Catherine E. Myers, Diane Hill, Michael A. Yassa, and Mark A. Gluck. ABCA7 Risk Variant in Healthy Older African Americans is Associated with a Functionally Isolated Entorhinal Cortex Mediating Deficient Generalization of Prior Discrimination Training. Hippocampus, 29(6):527-538, Jun 2019. (pubmed)

61. Xue Feng, Kun Qing, Nicholas J. Tustison, Craig H. Meyer, and Quan Chen. Deep convolutional neural network for segmentation of thoracic organs-at-risk using cropped 3D images. Medical Physics, 46(5):2169-2180, May 2019. (pubmed)

60. Nasreen Sayed, Changho Choi, Nicholas Tustison, Jared Roberts, Michael Yassa, Erin Van Enkevort, Alyson Nakamura, Elena I Ivleva, Prabha Sunderajan, David A Khan, Miguel Vazquez, Bruce McEwen, Alexandra Kulikova, Traci Holmes, and Sherwood Brown. A Randomized, Double-Blind, Placebo-Controlled Trial of Lamotrigine for Prescription Corticosteroid Effects on the Human Hippocampus, European Neuropsychopharmacology, 29(3):376-383, Mar 2019. (pubmed)

59. Nicholas J. Tustison, Brian B. Avants, Zixuan Lin, Xue Feng, Nicholas Cullen, Jaime F. Mata, Lucia Flors, James C. Gee, Talissa A. Altes, John P. Mugler III, and Kun Qing. Convolutional Neural Networks with Template-Based Data Augmentation for Functional Lung Image Quantification, Academic Radiology, 26(3):412-423, Mar 2019. (pubmed)

58. K Qing, NJ Tustison, JP Mugler 3rd, JF Mata, Z Lin, L Zhao, D Wang, X Feng, JY Shin JY, SJ Callahan, MP Bergman, K Ruppert, TA Altes, JM Cassani, and YM Shim. Probing Changes in Lung Physiology in COPD Using CT, Perfusion MRI, and Hyperpolarized Xenon-129 MRI, Academic Radiology, 26(3):326-334, Mar 2019. (pubmed)


57. Andrew T. Grainger, Nicholas J. Tustison, Kun Qing, Rene Roy, Stuart S. Berr, and Weibin Shi. Deep learning-based quantification of abdominal fat on magnetic resonance images. PLoS One, 13(9):e0204071, Sep 2018. (pubmed)

56. Yi Xin, Maurizio Cereda, Hooman Hamedani, Mehrdad Pourfathi, Sarmad Siddiqui, Natalie Meeder, Stephen Kadlacek, Ian Duncan, Harrilla Profka, Jennia Rajaei, Nicholas Tustison, James Gee, Brian Kavanagh, and Rahim Rizi. Unstable Inflation Causing Injury: Insight from Prone Position and Paired CT Scans, American Journal of Respiratory and Critical Care Medicine, 198(2):197-207, Jul 2018. (pubmed)

55. Neha Sinha, Chelsie N., Berg, Nicholas J. Tustison, Ashlee Shaw, Diane Hill, Michael A. Yassa, and Mark A. Gluck. APOE ε4 Status in Healthy Older African Americans is Associated with Deficits in Pattern Separation and Hippocampal Hyperactivation, Neurobiology of Aging, 26;69:221-229, May 2018. (pubmed)

54. Zachariah M. Reagh, Jessica A. Noche, Nicholas J. Tustison, Derek Delisle, Elizabeth A. Murray, and Michael A. Yassa. Functional Imbalance of Anterolateral Entorhinal Cortex and Hippocampal Dentate/CA3 Underlies Age-Related Object Pattern Separation Deficits, Neuron, 97(5):1187-1198, Mar 2018. (pubmed)

53. E. Mortani Barbosa Jr., H. Shou, S. Simpson, J. Gee, N. Tustison, and J.C. Lee, Quantitative CT metrics from the transplanted lung can predict FEV1 after lung transplantation, Journal of Thoracic Imaging, 33(2):112-123, Mar 2018. (pubmed)

52. Sandhitsu Das, Long Xie, Laura Wisse, Ranjit Ittyerah, Nicholas Tustison, Bradford Dickerson, Paul Yushkevich, and David Wolk. Longitudinal and cross-sectional structural magnetic resonance imaging correlates of AV-1451 uptake, Neurobiology of Aging, 66:49-58, Feb 2018. (pubmed)


51. Maurizio Cereda, Yi Xin, Hooman Hamedani, Giacomo Bellani, Stephen Kadlecek, Justin Clapp, Luca Guerra, Natalie Meeder, Jennia Rajaei, Nicholas J. Tustison, James C. Gee Brian P. Kavanagh, and Rahim R. Rizi. Tidal Changes on CT and Progression of ARDS, Thorax, 72(11):981-989, Nov 2017. (pubmed)

50. E. Mortani Barbosa Jr., S. Simpson, J.C. Lee, N. Tustison, J. Gee, and H. Shou, Multivariate modeling using quantitative CT metrics may improve accuracy of diagnosis of bronchiolitis obliterans syndrome after lung transplantation, Computers in Biology and Medicine, 89:275-281, Oct 2017. (pubmed)

49. A. Murat Maga, Nicholas J. Tustison, and Brian B. Avants. A population level atlas of Mus musculus craniofacial skeleton and automated image based shape analysis, Journal of Anatomy, 231(3):433-443, Sep 2017. (pubmed)

48. Beau Pontré, Brett R. Cowan, Edward DiBella, Sancgeetha Kulaseharan, Devavrat Likhite, Nils Noorman, Lennart Tautz, Nicholas Tustison, Gert Wollny, Alistair A. Young, and Avan Suinesiaputra. An Open Benchmark Challenge for Motion Correction of Myocardial Perfusion MRI, IEEE Journal of Biomedical and Health Informatics, 21(5):1315-1326, Sep 2017. (pubmed)

47. Amy C. Ladd, David G. Browhan, Ravindar R. Thomas, Paula M. Keeney, Stuart B. Berr, Shaharyar M. Khan, Francisco R. Portell, Meiram Z. Shakenov, Patrick F. Antkowiak, Bijoy Kundu, Nicholas J. Tustison, James P. Bennett, Jr. RNA-seq Analyses Reveal that Cervical Spinal Cords and Anterior Motor Neurons from Amyotrophic Lateral Sclerosis Subjects Show Reduced Expression of Mitochondrial DNA-Encoded Respiratory Genes, and rhTFAM May Correct This Respiratory Deficiency, Brain Research 1667:74-83, Jul 2017. (pubmed)

46. Talissa A. Altes, Mac Johnson, Meredith Fidler, Martyn Botfield, Nicholas J. Tustison, Carlos Leiva-Salinas, Eduard E. de Lange, Deborah Froh, and John P. Mugler III. Use of hyperpolarized helium-3 MRI to assess response to ivacaftor treatment in patients with cystic fibrosis, Journal of Cystic Fibrosis, 16(2):267-274, Mar 2017. (pubmed)


45. Elisabeth A. Wilde, Erin D. Bigler, Trevor J. Huff, Haonan Wang, Garrett M. Black, Zachary Christensen, Naomi Goodrich-Hunsaker, Jo Ann Petrie, Tracy Abildskov, Brian A. Taylor, James R. Stone, Nicholas J. Tustison, Mary R. Newsome, Harvey S. Levin, Zili D. Chu, Gerald E. York, David F. Tate. Quantitative Structural Neuroimaging of Mild Traumatic Brain Injury in the Chronic Effects of Neurotrauma Consortium (CENC): Comparison of Volumetric Data within and across Scanners, Brain Injury, 30(12):1442-1451, 2016. (pubmed)

44. James R. Stone, Elisabeth A. Wilde, Brian A. Taylor, David F. Tate, Harvey Levin, Erin D. Bigler, Randall S. Scheibel, Mary R. Newsome, Andrew R. Mayer, Tracy Abildskov, Garrett M. Black4, Michael J. Lennon, Gerald E. York, Rajan Agarwal, Jorge DeVillasante, John L. Ritter, Peter B. Walker, Stephen T. Ahlers, and Nicholas J. Tustison. Supervised learning technique for the automated identification of white matter hyperintensities in traumatic brain injury, Brain Inury, 30(12):1458-1468, 2016. (pubmed)

43. Lucia Flors, John P. Mugler, Eduard E. De Lange, Grady W. Miller, Jaime F. Mata, Nick Tustison, Iulian C. Ruset, William W. Hersman, and Talissa A. Altes. Hyperpolarized Gas Magnetic Resonance Lung Imaging in Children and Young Adults, J Thorac Imaging, 31(5):285-95, Sep 2016. (pubmed)

42. Anthony J. Filiano, Yang Xu, Nicholas J. Tustison, Rachel L. Marsh, Wendy Baker, Igor Smirnov, Christopher C. Overall, Sachin P. Gadani, Stephen D. Turner, Zhiping Weng, Sayeda Najamussahar Peerzade, Hao Chen, Kevin S. Lee, Michael M. Scott, Mark P. Beenhakker, Vladimir Litvak, and Jonathan Kipnis. Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour, Nature, 535(7612):425-9, Jul 2016. (pubmed)

41. Nicholas J. Tustison, Kun Qing, Chengbo Wang, Talissa A. Altes, John P. Mugler III. Atlas-based estimation of lung and lobar anatomy in proton MRI. Magn Reson Med, 76(1):315-20, Jul 2016. (pubmed)

40. Genevera I Allen, Nicola Amoroso, Catalina Anghel, Venkat Balagurusamy, Christopher J Bare, Derek Beaton, Roberto Bellotti, David A Bennett, Kevin Boehme, Paul C Boutros, Laura Caberlotto, Cristian Caloian, Frederick Campbell, Elias Chaibub Neto, Yu- Chuan Chang, Beibei Chen, Chien-Yu Chen, Ting-Ying Chien, Tim Clark, Sudeshna Das, Christos Davatzikos, Jieyao Deng, Donna Dillenberger, Richard JB Dobson, Qilin Dong, Jimit Doshi, Denise Duma, Rosangela Errico, Guray Erus, Evan Everett, David W Fardo, Stephen H Friend, Holger Fröhlich, Jessica Gan, Peter St George-Hyslop, Satrajit S Ghosh, Enrico Glaab, Robert C Green, Yuanfang Guan, Ming-Yi Hong, Chao Huang, Jinseub Hwang, Joseph Ibrahim, Paolo Inglese, Qijia Jiang, Yuriko Katsumata, John SK Kauwe, Arno Klein, Dehan Kong, Roland Krause, Emilie Lalonde, Mario Lauria, Eunjee Lee, Xihui Lin, Zhandong Liu, Julie Livingstone, Benjamin A Logsdon, Simon Lovestone, Anandhi Lyappan, Michelle Ma, Ashutosh Malhotra, Lara M Mangravite, Taylor J Maxwell, Emily Merrill, John Nagorski, Aishwarya Namasivayam, Manjari Narayan, Mufassra Naz, Stephen J Newhouse, Thea C Norman, Ramil N Nurtdinov, Yen-Jen Oyang, Yudi Pawitan, Shengwen Peng, Mette A Peters, Stephen R Piccolo, Paurush Praveen, Corrado Priami, Veronica Y Sabelnykova, Philipp Senger, Xia Shen, Andrew Simmons, Aristeidis Sotiras, Gustavo Stolovitzky, Sabina Tangaro, Andrea Tateo, Yi-An Tung, Nicholas J Tustison, Erdem Varol, George Vradenburg, Michael W Weiner, Guanghua Xiao, Lei Xie, Yang Xie, Jia Xu, Hojin Yang, Xiaowei Zhan, Yunyun Zhou, Fan Zhu, Hongtu Zhu, Shanfeng Zhu, Alzheimer’s Disease Neuroimaging Initiative. Crowdsourced estimation of cognitive decline and resilience in Alzheimer’s disease. Alzheimers Dement, 12(6):645-53, Jun 2016. (pubmed)

39. Khader M. Hasan, Benson Mwangi, Bo Cao, Zafer Keser, Nicholas J. Tustison, Peter Kochunov, Richard E. Frye, Mirjana Savatic, Jair Soares. Entorhinal cortex thickness across the human lifespan. J of Neuroimaging, 26(3):278-82, May 2016. (pubmed)

38. Dorian Pustina, Branch H Coslett, Peter E Turkeltaub, Nicholas Tustison, Myrna F Schwartz, and Brian Avants. Automated segmentation of chronic stroke lesions using LINDA: Lesion Identification with Neighborhood Data Analysis, Hum Brain Mapp, 37(4):1405-21, Apr 2016. (pubmed)

37. Talissa A. Altes, John P. Mugler III, Kai Ruppert, Nicholas J. Tustison, Joanne Gersbach, Sylvia Szentpetery, Craig H. Meyer, Eduard E. de Lange, and W. Gerald Teague. Clinical Correlates of Lung Ventilation in Asthmatic Children. J Allergy Clin Immun, 137(3):789-796, Mar 2016. (pubmed)


36. Kun Qing, Talissa A. Altes, Nicholas J. Tustison, Xue Feng, Xiao Chen, Jaime F. Mata, G. Wilson Miller, Eduard E. de Lange, William A. Tobias, Gordon D. Cates, Jr., James R. Brookeman, John P. Mugler, III. Rapid Acquisition of Helium-3 and Proton 3D Image Sets of the Human Lung in a Single Breath-hold using Compressed Sensing. Magn Reson Med, 74(4):1110-5, Oct 2015. (pubmed)

35. Bjoern H. Menze, Andras Jakab, Stefan Bauer, Jayashree Kalpathy-Cramer, Keyvan Farahani, Justin Kirby, Yuliya Burren, Nicole Porz, Johannes Slotboom, Roland Wiest, Levente Lanczi, Elizabeth Gerstner, Marc-Andre Weber, Tal Arbel, Brian B. Avants, Nicholas Ayache, Patricia Buendia, D. Louis Collins, Nicolas Cordier, Jason J. Corso, Antonio Criminisi, Tilak Das, Herve ́ Delingete, Cagatay Demiralp, Christopher R. Durst, Michel Dojat, Senan Doyle, Joana Festa, Florence Forbes, Ezequiel Geremia, Ben Glocker, Polina Golland, Xiaotao Guo, Andac Hamamci, Khan M. Iftekharuddin, Raj Jena, Nigel M. John, Ender Konukoglu, Danial Lashkari, Jose Antonio Mariz, Raphael Meier, Sergio Pereira, Doina Precup, S. J. Price, Tammy Riklin-Raviv, Syed M. S. Reza, Michael Ryan, Lawrence Schwartz, Hoo-Chang Shin, Jamie Shotton, Carlos A. Silva, Nuno Sousa, Nagesh K. Subbanna, Gabor Szekely, Thomas J. Taylor, Owen M. Thomas, Nicholas J. Tustison, Gozde Unal, Flor Vasseur, Max Wintermark, Dong Hye Ye, Liang Zhao, Binsheng Zhao, Darko Zikic, Marcel Prastawa, Mauricio Reyes, and Koen Van Leemput. The Multimodal Brain Tumor Image Segmentation Benchmark (BRATS). IEEE Trans Med Imaging, 34(10):1993-2024, Oct 2015. (pubmed)

34. CR Durst, N Michael, NJ Tustison, JT Patrie, P Raghavan, M Wintermark, SS Velan. Noninvasive Evaluation of the Regional Variations of GABA using Magnetic Resonance Spectroscopy at 3 Tesla. Magn Reson Imaging, 33(5):611-7, June 2015. (pubmed)

33. Nicholas J. Tustison, K. L. Shrinhidi, Max Wintermark, Christopher R. Durst, Benjamin M. Kandel, James C. Gee, Murray C. Grossman, and Brian B. Avants. Optimal symmetric multimodal templates and concatenated random forests for supervised brain tumor segmentation (simplified) with ANTsR. Neuroinformatics, 13(2):209-225, April 2015. (pubmed)

32. Brian B. Avants, Hans J. Johnson, Nicholas J. Tustison. Neuroinformatics and the Insight ToolKit. Front Neuroinform, 9:5, March 2015. (pubmed)

31. Yi Xin, Gang Song, Maurizio Cereda, Stephen Kadlecek, Hooman Hamedani, Yunqing Jiang, Jennia Rajaei, Justin Clapp, Harrilla Profka, Natalie Meeder, Jue Wu, Nicholas Tustison, James Gee, and Rahim Rizi. Semi-Automatic Segmentation of Longitudinal Computed Tomography Images in a Rat Model of Lung Injury by Surfactant Depletion. J Appl Physiol, 118(3):377-85, Feb 2015. (pubmed)

30. Brian Avants, Jeffrey Duda, Emily Kilroy, Kay Jann, Benjamin Kandel, Lirong Yan, Mayank Jog, Nicholas Tustison, Robert Smith, Yi Wang, Kate Krasileva, Mirella Rapretto, and Danny Wang. The Pediatric Template of Brain Perfusion, Scientific Data, Feb 2015. (pubmed)


29. Jonathon H Yoder, John M Peloquin, Gang Song, Nicholas J Tustison, Sung M Moon, Alexander C Wright, Edward J Vresilovic, James C Gee, Dawn M Elliott. Internal Human Intervertebral Disc 3D Strains Under Axial Compression Quantified Non-invasively with MRI and Image Registration. J Biomech Eng, 136(11), Nov 2014. (pubmed)

28. Nicholas Said, W. Jeff Elias, Prashant Raghavan, Alan Cupino, Nicholas Tustison, Robert Frysinger, James Patrie, Wenjun Xin, Max Wintermark. Correlation of Diffusion Tensor Tractography and Intraoperative Macro-Stimulation during Deep Brain Stimulation for Parkinson’s Disease. J Neurosurg, 25:1-7, Jul 2014. (pubmed)

27. Nicholas J. Tustison, Philip A. Cook, Arno Klein, Gang Song, Sandhitsu R. Das, Jeffrey T. Duda, Benjamin M. Kandel, Niels van Strien, James R. Stone, James C. Gee, and Brian B. Avants. Large-Scale Evaluation of ANTs and FreeSurfer Cortical Thickness Measurements. NeuroImage, 99:166-179, Oct 2014. (pubmed)

26. Max Wintermark, Nicholas J Tustison, William J Elias, James T Patrie, Wenjun Xin, Nicholas Demartini, Matt Eames, Suna Sumer, Benison Lau, Alan Cupino, John Snell, Arik Hananel, Neal Kassell, and Jean-Francois Aubry. T1-weighted MRI as a substitute to CT for refocusing planning in MR-guided focused ultrasound. Phys Med Biol, 59(13):3599-614, July 2014. (pubmed)

25. W. Gerald Teague, Nicholas J. Tustison, and Talissa A. Altes. Ventilation Heterogeneity in Asthma. Journal of Asthma, 13:1-30, May 2014. (pubmed)

24. Brian B. Avants, Nicholas J. Tustison, Michael Stauffer, Gang Song, Baohua Wu, and James C. Gee. The Insight ToolKit Image Registration Framework. Front Neuroinform, 8:44. (pubmed)

23. Max Wintermark, Diane S. Huss, Binit B. Shah, Nicholas J. Tustison, T. Jason Druzgal, Neal Kassell, and Jeff Elias. Thalamic Connectivity in Patients with Essential Tremor Treated with MR Imaging-guided Focused Ultrasound: In Vivo Fiber Tracking by Using Diffusion-Tensor MR Imaging. Radiology, 272(1):202-9, Jul 2014. (pubmed)

22. Nicholas J Tustison, Brian B Avants, Philip A Cook, Junghoon Kim, John Whyte, James C Gee, and James R Stone. Logical circularity in voxel-based analysis: Normalization strategy may induce statistical bias. Hum Brain Mapp, 35:745–759, Mar 2014. (pubmed)

21. Christopher R Durst, Prashant Raghavan, Mark E Shaffrey, David Schiff, M Beatriz Lopes, Jason P Sheehan, Nicholas J Tustison, James T Patrie, Wenjun Xin, W Jeff Elias, Kenneth C Liu, Greg A Helm, A Cupino, and Max Wintermark. Multimodal MR imaging model to predict tumor infiltration in patients with gliomas. Neuroradiology, 56(2):107-15, Feb 2014. (pubmed)


20. Nicholas J. Tustison and Brian B. Avants. Explicit B-spline regularization in diffeomorphic image registration. Front Neuroinform, 7:39, 2013. (pubmed)

19. Nicholas J Tustison, Hans J Johnson, Torsten Rohlfing, Arno Klein, Satrajit S Ghosh, Luis Ibanez, and Brian B Avants. Instrumentation bias in the use and evaluation of scientific software: recommendations for reproducible practices in the computational sciences. Front Neurosci, 7:162, 2013. (pubmed)


18. Gang Song, Eduardo Mortani Barbosa, Jr, Nicholas Tustison, Warren B Gefter, Maryl Kreider, James C Gee, and Drew A Torigian. A comparative study of HRCT image metrics and PFT values for characterization of ILD and COPD. Acad Radiol, 19(7):857–64, Jul 2012. (pubmed)


17. Brian B Avants, Nicholas J Tustison, Jue Wu, Philip A Cook, and James C Gee. An open source multivariate framework for n-tissue segmentation with evaluation on public data. Neuroinformatics, 9(4):381–400, Dec 2011. (pubmed)

16. Keelin Murphy, Bram van Ginneken, Joseph M Reinhardt, Sven Kabus, Kai Ding, Xiang Deng, Kunlin Cao, Kaifang Du, Gary E Christensen, Vincent Garcia, Tom Vercauteren, Nicholas Ayache, Olivier Commowick, Grégoire Malandain, Ben Glocker, Nikos Paragios, Nassir Navab, Vladlena Gorbunova, Jon Sporring, Marleen de Bruijne, Xiao Han, Mattias P Heinrich, Julia A Schnabel, Mark Jenkinson, Cristian Lorenz, Marc Modat, Jamie R McClelland, Sébastien Ourselin, Sascha E A Muenzing, Max A Viergever, Dante De Nigris, D Louis Collins, Tal Arbel, Marta Peroni, Rui Li, Gregory C Sharp, Alexander Schmidt-Richberg, Jan Ehrhardt, René Werner, Dirk Smeets, Dirk Loeckx, Gang Song, Nicholas Tustison, Brian Avants, James C Gee, Marius Staring, Stefan Klein, Berend C Stoel, Martin Urschler, Manuel Werlberger, Jef Vandemeulebroucke, Simon Rit, David Sarrut, and Josien P W Pluim. Evaluation of registration methods on thoracic CT: the EMPIRE10 challenge. IEEE Trans Med Imaging, 30(11):1901–20, Nov 2011. (pubmed)

15. Eduardo Mortani Barbosa, Jr, Gang Song, Nicholas Tustison, Maryl Kreider, James C Gee, Warren B Gefter, and Drew A Torigian. Computational analysis of thoracic multidetector row HRCT for segmentation and quantification of small airway air trapping and emphysema in obstructive pulmonary disease. Acad Radiol, 18(10):1258–69, Oct 2011. (pubmed)

14. Nicholas J Tustison, Brian B Avants, Lucia Flors, Talissa A Altes, Eduard E de Lange, John P Mugler, 3rd, and James C Gee. Ventilation-based segmentation of the lungs using hyperpolarized (3)he MRI. J Magn Reson Imaging, 34(4):831–41, Oct 2011. (pubmed)

13. Cuneyt Yilmaz, Nicholas J Tustison, D Merrill Dane, Priya Ravikumar, Masaya Takahashi, James C Gee, and Connie C W Hsia. Progressive adaptation in regional parenchyma mechanics following extensive lung resection assessed by functional computed tomography. J Appl Physiol, 111(4):1150–8, Oct 2011. (pubmed)

12. Nicholas J Tustison, Brian B Avants, Marcelo Siqueira, and James C Gee. Topological well-composedness and glamorous glue: a digital gluing algorithm for topologically constrained front propagation. IEEE Trans Image Process, 20(6):1756–61, Jun 2011. (pubmed)

11. Nicholas J Tustison, Tessa S Cook, Gang Song, and James C Gee. Pulmonary kinematics from image data: a review. Acad Radiol, 18(4):402–17, Apr 2011. (pubmed)

10. Brian B Avants, Nicholas J Tustison, Gang Song, Philip A Cook, Arno Klein, and James C Gee. A reproducible evaluation of ANTs similarity metric performance in brain image registration. Neuroimage, 54(3):2033–44, Feb 2011. (pubmed)

9. Nicholas J Tustison, Suyash P Awate, Gang Song, Tessa S Cook, and James C Gee. Point set registration using Havrda-Charvat-Tsallis entropy measures. IEEE Trans Med Imaging, 30(2):451–60, Feb 2011. (pubmed)


8. Nicholas J Tustison, Talissa A Altes, Gang Song, Eduard E de Lange, John P Mugler, 3rd, and James C Gee. Feature analysis of hyperpolarized helium-3 pulmonary MRI: a study of asthmatics versus nonasthmatics. Magn Reson Med, 63(6):1448–55, Jun 2010. (pubmed)

7. Nicholas J Tustison, Brian B Avants, Philip A Cook, Yuanjie Zheng, Alexander Egan, Paul A Yushkevich, and James C Gee. N4ITK: improved N3 bias correction. IEEE Trans Med Imaging, 29(6):1310–20, Jun 2010. (pubmed)

6. Nicholas J Tustison, Suyash P Awate, Jing Cai, Talissa A Altes, G Wilson Miller, Eduard E de Lange, John P Mugler, 3rd, and James C Gee. Pulmonary kinematics from tagged hyperpolarized helium-3 MRI. J Magn Reson Imaging, 31(5):1236–41, May 2010. (pubmed)


5. Nicholas J Tustison, Brian B Avants, and James C Gee. Directly manipulated free-form deformation image registration. IEEE Trans Image Process, 18(3):624–35, Mar 2009. (pubmed)


4. Marcelo Siqueira, Longin J. Latecki, Nicholas J. Tustison, J. Gallier, and James C. Gee. Topological repairing of 3D digital images. J Math Imaging Vis, 30(3):249–274, March 2008.


3. Nicholas J. Tustison and Amir A. Amini. Biventricular myocardial strains via nonrigid registration of anatomical NURBS model [corrected]. IEEE Trans Med Imaging, 25(1):94–112, Jan 2006. (pubmed)


2. Nicholas J Tustison, Victor G Dávila-Román, and Amir A Amini. Myocardial kinematics from tagged MRI based on a 4-D B-spline model. IEEE Trans Biomed Eng, 50(8):1038–40, Aug 2003. (pubmed)


1. K D Hagspiel, T A Altes, J P Mugler, 3rd, M J Spellman, Jr, J F Mata, N J Tustison, and J R Brookeman. MR virtual colonography using hyperpolarized (3)He as an endoluminal contrast agent: demonstration of feasibility. Magn Reson Med, 44(5):813–6, Nov 2000. (pubmed)